Unmixing for ultra-high-plex fluorescence imaging.
Where this comes from
- Record sourced from PubMed, PMID 35710800.
- Also identified by DOI 10.1038/s41467-022-31110-z and PMC identifier 9203536.
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Abstract
Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy.
Medical subject headings
- Optical Imaging