Durability of Immune Responses After Boosting in Ad26.COV2.S-Primed Healthcare Workers.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 35723273.
- Also identified by DOI 10.1093/cid/ciac495 and PMC identifier 9384313.
- Licence recorded as CC BY-NC-ND.
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Abstract
The emergence of SARS-CoV-2 variants raised questions regarding the durability of immune responses after homologous or heterologous boosters after Ad26.COV2.S-priming. We found that SARS-CoV-2-specific binding antibodies, neutralizing antibodies, and T cells are detectable 5 months after boosting, although waning of antibodies and limited cross-reactivity with Omicron BA.1 was observed.
Medical subject headings
- Ad26COVS1
- COVID-19