Gut Microbiome Redox Sensors With Ultrasonic Wake-Up and Galvanic Coupling Wireless Links.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35727787.
- Also identified by DOI 10.1109/TBME.2022.3184972 and PMC identifier 9911315.
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Abstract
Tools to measure in vivo redox activity of the gut microbiome and its influence on host health are lacking. In this paper, we present the design of new in vivo gut oxidation-reduction potential (ORP) sensors for rodents, to study host-microbe and microbe-environment interactions throughout the gut. These are the first in vivo sensors to combine ultrasonic wake-up and galvanic coupling telemetry, allowing for sensor miniaturization, experiment flexibility, and robust wireless measurements in live rodents. A novel study of in situ ORP along the intestine reveals biogeographical redox features that the ORP sensors can uniquely access in future gut microbiome studies.
Medical subject headings
- Ultrasonics
- Gastrointestinal Microbiome