Transcriptome, connectome and neuromodulation of the primate brain.

Poo, Mu-Ming · Cell · 2022

basic_science · Level V

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Abstract

Single-cell transcriptomic analysis has facilitated cell type identification in the brain and mapping of cell type-specific connectomes, helping to elucidate neural circuits underlying brain functions and to treat brain disorders by neuromodulation. Yet, we lack a consensual definition of neuronal types/subtypes and clear distinction between cause and effect within interconnected networks.

Medical subject headings