Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35736814.
- Also identified by DOI 10.1158/1078-0432.CCR-22-1255 and PMC identifier 9444945.
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Abstract
A recent study reported results from a clinical trial in cats and from experiments in mini-pigs in which a single dose of radiotherapy was delivered at ultrahigh dose rates (FLASH). There was acceptable acute toxicity; however, some animals suffered severe late toxicity, raising caution in the design of future trials. See related article by Rohrer Bley et al., p. 3814.
Medical subject headings
- Carcinoma, Squamous Cell
- Radiation Oncology