A behavioural study of hydrothermally derived novel alumina/magnesia/hydroxyapatite (Al<sub>2</sub>O<sub>3</sub>/MgO/HA) bioceramic nanocomposite.
biomechanical · Level V
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- Record sourced from PubMed, PMID 35749932.
- Also identified by DOI 10.1016/j.jmbbm.2022.105313.
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Abstract
Regeneration and regrowth of human bones is a gradual and time-consuming process. Therefore scaffolds are required to hold the bones in position and give them time to heal well. Though hydroxyapatite (HA) is a potential candidate, its weak mechanical nature has made it undesirable. To overcome this hurdle, a novel nanocomposite of HA with alumina (Al<sub>2</sub>O<sub>3</sub>) and magnesia (MgO) was prepared by hydrothermal method in this study. The constitution, composition and conformation of the Al<sub>2</sub>O<sub>3</sub>/MgO/HA nanocomposite were affirmed via X-ray Diffraction (XRD), Fourier-Transform Infra-Red (FTIR) and imaging tests. Vicker's hardness test evinces the mechanical calibre of the nanocomposite. A perspective load-displacement analysis was done by means of Onitsch and Kick's power laws. The nanocomposite excelled above par with a hardness of 5.19 GPa and fracture toughness of 1.27 MPam<sup>1/2</sup>. This holistic progress makes this nanocomposite a very desirable bone implant material.
Medical subject headings
- Durapatite
- Nanocomposites