Mirage 2.0: fast and memory-efficient reconstruction of gene-content evolution considering heterogeneous evolutionary patterns among gene families.
Where this comes from
- Record sourced from PubMed, PMID 35771653.
- Also identified by DOI 10.1093/bioinformatics/btac433 and PMC identifier 9364385.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We present Mirage 2.0, which accurately estimates gene-content evolutionary history by considering heterogeneous evolutionary patterns among gene families. Notably, we introduce a deterministic pattern mixture model, which makes Mirage substantially faster and more memory-efficient to be applicable to large datasets with thousands of genomes. The source code is freely available at https://github.com/fukunagatsu/Mirage. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software
- Genome