Segmentation only uses sparse annotations: Unified weakly and semi-supervised learning in medical images.

Gao, Feng; Hu, Minhao; Zhong, Min-Er; Feng, Shixiang; Tian, Xuwei; Meng, Xiaochun; Ni-Jia-Ti, Ma-Yi-di-Li; Huang, Zeping et al. · Med Image Anal · 2022

basic_science · Level V

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Abstract

Since segmentation labeling is usually time-consuming and annotating medical images requires professional expertise, it is laborious to obtain a large-scale, high-quality annotated segmentation dataset. We propose a novel weakly- and semi-supervised framework named SOUSA (Segmentation Only Uses Sparse Annotations), aiming at learning from a small set of sparse annotated data and a large amount of unlabeled data. The proposed framework contains a teacher model and a student model. The student model is weakly supervised by scribbles and a Geodesic distance map derived from scribbles. Meanwhile, a large amount of unlabeled data with various perturbations are fed to student and teacher models. The consistency of their output predictions is imposed by Mean Square Error (MSE) loss and a carefully designed Multi-angle Projection Reconstruction (MPR) loss. Extensive experiments are conducted to demonstrate the robustness and generalization ability of our proposed method. Results show that our method outperforms weakly- and semi-supervised state-of-the-art methods on multiple datasets. Furthermore, our method achieves a competitive performance with some fully supervised methods with dense annotation when the size of the dataset is limited.

Medical subject headings