A new role for ammonia in tumorigenesis?
Where this comes from
- Record sourced from PubMed, PMID 35793658.
- Also identified by DOI 10.1016/j.cmet.2022.06.009.
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Abstract
Tumor-supporting roles of ammonia have gained greater appreciation in recent years and normally focus on ammonia's role as a nitrogen source. Recently in Nature Metabolism,Cheng et al. (2022) demonstrate a novel, non-nitrogen, metabolism-related role of ammonia as a key activator for lipogenesis by facilitating SREBP-1 activation.
Medical subject headings
- Ammonia
- Carcinogenesis