Safety of High-Dose Nasal Theophylline Irrigation in the Treatment of Postviral Olfactory Dysfunction: A Dose-Escalation Study.

Lee, Jake J; Gupta, Shruti; Kallogjeri, Dorina; Piccirillo, Jay F · JAMA Otolaryngol Head Neck Surg · 2022

case_series · Level IV

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Abstract

This case series aims to determine the maximum tolerable dose of theophylline delivered via high-volume, low-pressure nasal saline irrigation for treatment of postviral olfactory dysfunction.

Medical subject headings