Effects of COVID-19 during pregnancy on maternal and neonatal outcome: A retrospective observational study in tertiary teaching hospital, India.

Kumari, Archana; Anand, Shikha; Vidyarthi, Anubha · J Family Med Prim Care · 2022

retrospective_cohort · Level III

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Abstract

This study aims to describe the clinical characteristics, maternal and neonatal outcome of pregnancies complicated with COVID-19 infection. This is a retrospective, single center, observational study conducted on all COVID-19 positive pregnant women who were admitted in our institution from 1<sup>st</sup> April 2020 to 30<sup>th</sup> November 2020. During the study period, a total of 201 pregnant and postpartum women with COVID-19 infection confirmed by RT-PCR test, regardless of their symptoms, were admitted and included in the study. Data were collected from hospital records about the demographic profile, clinical characteristics, maternal and neonatal outcomes. The mean age was 26 years (SD = 5.21). Majority patients (71.6%) were asymptomatic and 22.3% had mild symptoms. Only 4 (1.99%) women had severe COVID pneumonia. Majority (75.62%) were admitted in 3<sup>rd</sup> trimester. Cesarean section rate in COVID-19 infected pregnant women was 53.8%, which was almost similar to 52.8% rate in COVID-19 negative pregnant population. Incidence of preterm birth was 11%. Most neonate were asymptomatic and only 2 of them tested positive on testing within 48 h of birth. There is no major effect of COVID-19 infection during pregnancy on maternal and neonatal outcome. The incidence of preterm birth and cesarean section is similar to COVID-19 negative pregnant population.