Taming the transposon: H3K9me3 turns foe to friend in human development.
editorial · Level V
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- Record sourced from PubMed, PMID 35803220.
- Also identified by DOI 10.1016/j.stem.2022.06.010 and PMC identifier 9484580.
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Abstract
In this issue of Cell Stem Cell, Xu et al. and Yu et al. use low-input epigenetic profiling techniques to map H3K9me3 deposition in early human development. They reveal stage-specific H3K9me3 deposition on retrotransposons, which may play crucial cis-regulatory roles in early development.
Medical subject headings
- Epigenesis, Genetic
- Histones