Mini kidney organoids deliver maximal drug screening impact.

Dixon, Eryn E; Bradford, Shayna T J; Humphreys, Benjamin D · Cell Stem Cell · 2022

editorial · Level V

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Abstract

In this issue of Cell Stem Cell, Tran and colleagues develop a platform for differentiating thousands of miniature kidney organoids consisting of one or two nephron-like structures each. They use this platform to identify a potent new inhibitor of cyst growth in organoid models of autosomal-dominant polycystic kidney disease.

Medical subject headings