WNT Medulloblastoma Limbo: How Low Can We Go?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 35866882.
- Also identified by DOI 10.1158/1078-0432.CCR-22-1780.
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Abstract
Survival rates for average-risk medulloblastoma exceed 80%; however, long-term sequelae are substantial. A study from Mumbai, India evaluated the role of omission of craniospinal irradiation. Albeit unsuccessful, this study raises the crucial question of how low therapy can be safely de-escalated with the intent of improving quality of survival. See related article by Gupta et al., p. 4180.
Medical subject headings
- Cerebellar Neoplasms
- Craniospinal Irradiation
- Medulloblastoma