Cryo-electron tomography: A long journey to the inner space of cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35868271.
- Also identified by DOI 10.1016/j.cell.2022.06.034.
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Abstract
Cryogenic electron tomography (cryo-ET) is the application of tomographic principles of data acquisition and reconstruction to frozen-hydrated biological specimens. It combines a close-to-life preservation of cellular structures with the power of high-resolution three-dimensional imaging, which allows us to study the molecular architecture of cells, or their molecular sociology, in unprecedented detail.
Medical subject headings
- Electron Microscope Tomography
- Imaging, Three-Dimensional