Comparing radiolytic production of H<sub>2</sub>O<sub>2</sub> and development of Zebrafish embryos after ultra high dose rate exposure with electron and transmission proton beams.

Kacem, Houda; Psoroulas, Serena; Boivin, Gael; Folkerts, Michael; Grilj, Veljko; Lomax, Tony; Martinotti, Adrien; Meer, David et al. · Radiother Oncol · 2022

basic_science · Level V

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Abstract

The physico-chemical and biological response to conventional and UHDR electron and proton beams was investigated, along with conventional photons. The temporal structure and nature of the beam affected both, with electron beam at ≥1400 Gy/s and proton beam at 0.1 and 1260 Gy/s found to be isoefficient at sparing zebrafish embryos.

Medical subject headings