Proteomic discovery in diabetic kidney disease-to what end?

Rhee, Eugene P · Kidney Int · 2022

editorial · Level V

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Abstract

Emerging approaches that enable high-throughput analysis of the plasma proteome have been increasingly deployed in nephrology research. Kobayashi et al. provide a valuable addition to this literature, describing an untargeted proteomic analysis of diabetic kidney disease progression to end-stage kidney disease. This commentary places the study's findings in the context of the broader literature and outlines potential avenues toward biological insight and clinical utility.

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