Redifferentiation Therapy-Returning to Our Roots in a Post-Kinase Inhibitor World.

Cabanillas, Maria E; Busaidy, Naifa L; Sherman, Steven I · Clin Cancer Res · 2022

editorial · Level V

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Abstract

Radioactive iodine (RAI) treatment is an effective treatment for differentiated thyroid cancer (DTC); however, many patients are refractory. Using targeted drugs to reinduce RAI sensitivity ("redifferentiation therapy") has long been sought after as the holy grail in endocrine oncology. See related article by Weber et al., p. 4194.

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