Selection and characterisation of bioreceptors to develop nanoparticle-based lateral-flow immunoassays in the context of the SARS-CoV-2 outbreak.

Hu, Liming; Calucho, Enric; Fuentes-Chust, Celia; Parolo, Claudio; Idili, Andrea; Álvarez-Diduk, Ruslan; Rivas, Lourdes; Merkoçi, Arben · Lab Chip · 2022

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Abstract

This manuscript aims at raising the attention of the scientific community to the need for better characterised bioreceptors for fast development of point-of-care diagnostic devices able to support mass frequency testing. Particularly, we present the difficulties encountered in finding suitable antibodies for the development of a lateral flow assay for detecting the nucleoprotein of SARS-CoV-2.

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