A practical concept for catalytic carbonylations using carbon dioxide.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35908063.
- Also identified by DOI 10.1038/s41467-022-32030-8 and PMC identifier 9338997.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The rise of CO<sub>2</sub> in atmosphere is considered as the major reason for global warming. Therefore, CO<sub>2</sub> utilization has attracted more and more attention. Among those, using CO<sub>2</sub> as C1-feedstock for the chemical industry provides a solution. Here we show a two-step cascade process to perform catalytic carbonylations of olefins, alkynes, and aryl halides utilizing CO<sub>2</sub> and H<sub>2</sub>. For the first step, a novel heterogeneous copper 10Cu@SiO<sub>2</sub>-PHM catalyst exhibits high selectivity (≥98%) and decent conversion (27%) in generating CO from reducing CO<sub>2</sub> with H<sub>2</sub>. The generated CO is directly utilized without further purification in industrially important carbonylation reactions: hydroformylation, alkoxycarbonylation, and aminocarbonylation. Notably, various aldehydes, (unsaturated) esters and amides are obtained in high yields and chemo-/regio-selectivities at low temperature under ambient pressure. Our approach is of interest for continuous syntheses in drug discovery and organic synthesis to produce building blocks on reasonable scale utilizing CO<sub>2</sub>.