PanExplorer: a web-based tool for exploratory analysis and visualization of bacterial pan-genomes.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 35916725.
- Also identified by DOI 10.1093/bioinformatics/btac504 and PMC identifier 9477528.
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Abstract
As pan-genome approaches are largely employed for bacterial comparative genomics and evolution analyses, but still difficult to be carried out by non-bioinformatician biologists, there is a need for an innovative tool facilitating the exploration of bacterial pan-genomes. PanExplorer is a web application providing various genomic analyses and reports, giving intuitive views that enable a better understanding of bacterial pan-genomes. As an example, we produced the pan-genome for 121 Anaplasmataceae strains (including 30 Ehrlichia, 15 Anaplasma, 68 Wolbachia). PanExplorer is written in Perl CGI and relies on several JavaScript libraries for visualization (hotmap.js, MauveViewer, CircosJS). It is freely available at http://panexplorer.southgreen.fr. The source code has been released in a GitHub repository https://github.com/SouthGreenPlatform/PanExplorer. A documentation section is available on PanExplorer website.
Medical subject headings
- Genome, Bacterial
- Libraries