Melanin-Targeted PET Imaging Sheds Light on Pigment Epithelioma in Corpus Ciliare.
case_report · Level V
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- Record sourced from PubMed, PMID 35930712.
- Also identified by DOI 10.1097/RLU.0000000000004268.
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Abstract
A 57-year-old woman had gradually decreased visual acuity in the left eye, accompanied by distension and pain. MRI demonstrated a small neoplasm in corpus ciliare, which promoted PET imaging for further assessment. 18F-FDG PET imaging found no obvious uptake in the lesion. However, melanin-targeted PET imaging demonstrated the lesion with avid 18F-PFPN (18F-N-(2-diethylaminoethyl)-4-(2-[2-ethoxy]-ethoxy)pyridine) accumulation (SUVmax, 7.1), which suggested it with melanin expression. Pigmented epithelial adenoma was further confirmed by pathology. Our case illustrated that pigmented epithelial adenoma is characterized by avid 18F-PFPN accumulations and can be detected even in a hidden location with a size of ≤5 mm.
Medical subject headings
- Adenoma
- Carcinoma