Clinical Characteristics of Children with Cerebral Injury preceding Treatment of Diabetic Ketoacidosis.

Glaser, Nicole S; Quayle, Kimberly S; McManemy, Julie K; Nigrovic, Lise E; Tzimenatos, Leah; Stoner, Michael J; Bennett, Jonathan E; Trainor, Jennifer L et al. · J Pediatr · 2022

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Abstract

Previous studies have identified more severe acidosis and higher blood urea nitrogen (BUN) as risk factors for cerebral injury during treatment of diabetic ketoacidosis (DKA) in children; however, cerebral injury also can occur before DKA treatment. We found that lower pH and higher BUN levels also were associated with cerebral injury at presentation.

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