Impact of Seasonal Coronavirus Antibodies on Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Responses in Solid Organ Transplant Recipients.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 35959783.
- Also identified by DOI 10.1093/cid/ciac652 and PMC identifier 9384709.
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Abstract
Antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination are reduced in solid organ transplant recipients (SOTRs). We report that increased levels of preexisting antibodies to seasonal coronaviruses are associated with decreased antibody response to SARS-CoV-2 vaccination in SOTRs, supporting that antigenic imprinting modulates vaccine responses in SOTRs.
Medical subject headings
- COVID-19
- COVID-19 Vaccines
- Organ Transplantation
- Vaccines