Incidence and Clinical Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 Infection After Vaccination in Children.

Reyna, Megan E; Edward, Priya R; Ozer, Egon A; Simons, Lacy M; Hultquist, Judd F; Lorenzo-Redondo, Ramon; Patel, Ami B; Kociolek, Larry K · J Pediatr · 2022

prospective_cohort · Level II

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Abstract

The objective of this single-center cohort study was to characterize the frequency, clinical characteristics, and molecular epidemiology of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after vaccination. Between May 15, 2021, and January 1, 2022, 171 children experienced SARS-CoV-2 infection postvaccination, 146 (86%) following the Omicron variant predominance. Outcomes were generally mild and comparable before and after Omicron predominance.

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