Real-time optical oximetry during FLASH radiotherapy using a phosphorescent nanoprobe.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35964762.
- Also identified by DOI 10.1016/j.radonc.2022.08.011 and PMC identifier 11277691.
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Abstract
The rapid depletion of oxygen during irradiation at ultra-high dose rate calls for tissue oximeters capable of high temporal resolution. This study demonstrates a water-soluble phosphorescent nanoprobe and fiber-coupled instrument, which together are used to measure the kinetics of oxygen depletion at 200 Hz during irradiation of in vitro solutions.
Medical subject headings
- Oximetry
- Oxygen