Low Performance of Hepatitis Delta Virus Testing Among 2 National Cohorts of Chronic Hepatitis B Patients in the United States.

Wong, Robert J; Kaufman, Harvey W; Niles, Justin K; Chen, Cheng; Yang, Zeyuan; Kapoor, Hema; Cheung, Ramsey; Gish, Robert G · Am J Gastroenterol · 2022

retrospective_cohort · Level III

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Abstract

The purpose of this study was to evaluate hepatitis delta virus (HDV) testing patterns among US adults with chronic hepatitis B (CHB). HDV testing was evaluated among CHB patients using Quest Diagnostics (2016-2020) and Veterans Affairs (2010-2020) data. Among 157,333 CHB patients (Quest), 6.7% received HDV testing, among which 2.2% were positive. HDV testing was higher in male patients, younger individuals, and patients with advanced liver disease. Among 12,002 CHB patients (Veterans Affairs), 19.7% received HDV testing, among which 3.1% were positive. HDV testing was higher in younger individuals and Asians. Low HDV testing was observed among 2 large US cohorts of adults with CHB.

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