Evolution and Transmission of Cefiderocol-Resistant Acinetobacter baumannii During an Outbreak in the Burn Intensive Care Unit.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 35974429.
- Also identified by DOI 10.1093/cid/ciac647 and PMC identifier 10169418.
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Abstract
We report on 11 critically ill burn patients treated with cefiderocol for carbapenem-resistant Acinetobacter baumannii infections. Clinical success was achieved in 36% and complicated by treatment-emergent resistance and interpatient transmission of cefiderocol-resistant A. baumannii. Resistant isolates harbored disrupted pirA and piuA genes that were not disrupted among susceptible isolates.
Medical subject headings
- Acinetobacter baumannii
- Acinetobacter Infections