Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life.

Nelson, Bryan S; Tierney, Camlin; Persaud, Deborah; Jao, Jennifer; Cotton, Mark F; Bryson, Yvonne; Coletti, Anne; Ruel, Theodore D et al. · Clin Infect Dis · 2023

prospective_cohort · Level II

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Abstract

We followed 54 infants with in utero HIV after initiating very early antiretroviral treatment. At weeks 24 and 48, ≥80% had CD4 ≥1500 cells/mm3 and CD4% ≥25%. Routine Pneumocystis jirovecii pneumonia prophylaxis in the first year of life may not be necessary for all very early treated infants. NCT02140255.

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