Uncovering the origins and lineage markers of human heart fields.

Miyamoto, Matthew; Kwon, Chulan · Cell Stem Cell · 2022

basic_science · Level V

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Abstract

In this issue of Cell Stem Cell, Yang et al. devise a protocol for induction and differentiation of human heart-field precursors, drawing on inspiration from in vivo development. Intricate computational analyses uncovered conserved factors governing heart-field segregation, which facilitate enhanced study of human heart development and disease in the dish.

Medical subject headings