Fission impossible: Mitochondrial dynamics direct muscle stem cell fates.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 36055187.
- Also identified by DOI 10.1016/j.stem.2022.08.010.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Muscle stem cells (MuSCs) exhibit different metabolic profiles depending on their activity, however the mechanisms by which mitochondria affect MuSC fate has been understudied. In this issue of Cell Stem Cell, Hong et al. (2022) and Baker et al. (2022) demonstrate that defects in mitochondrial dynamics hinder proper MuSC activation and impair muscle regeneration.
Medical subject headings
- Mitochondrial Dynamics
- Muscle, Skeletal