Potential solutions for manufacture of CAR T cells in cancer immunotherapy.

Blache, Ulrich; Popp, Georg; Dünkel, Anna; Koehl, Ulrike; Fricke, Stephan · Nat Commun · 2022

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Abstract

CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the treatment of large patient groups.

Medical subject headings