The cAMP/PKA/CREB and TGFβ/SMAD4 Pathways Regulate Stemness and Metastatic Potential in Colorectal Cancer Cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36066360.
- Also identified by DOI 10.1158/0008-5472.CAN-22-1369.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
This study identifies signaling pathways essential for maintaining the stemness and metastatic potential of colorectal cancer cells and proposes CREB as a therapeutic target in metastatic colorectal cancer.
Medical subject headings
- Colorectal Neoplasms
- Neoplastic Stem Cells