Current and future approaches in the surgical management of T3b/T4 primary and locoregionally advanced melanoma.

Sondak, Vernon K; Neves, Rogerio I; Wuthrick, Evan J; Messina, Jane L; Khushalani, Nikhil I · Cancer · 2022

review · Level V

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Abstract

Currently accepted principles of surgical management-margin width, use of sentinel node biopsy, performance of radical node dissections for node-positive cases-and some aspects of postoperative management (use of radiation for desmoplastic melanoma primaries and for clinically node-positive disease) will change in the future with the potential widespread adoption of adjuvant and neoadjuvant therapies.

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