Methionine restriction forces Epstein-Barr virus out of latency.
Where this comes from
- Record sourced from PubMed, PMID 36070678.
- Also identified by DOI 10.1016/j.cmet.2022.08.009.
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Abstract
EBV gene expression is repressed during viral latency to prevent an immune response, but it is not known how metabolism contributes to this silencing. In this issue of Cell Metabolism, Guo et al. describe how methionine restriction reactivates the expression of EBV genes, offering new therapeutic approaches against EBV-driven diseases.
Medical subject headings
- Epstein-Barr Virus Infections
- Herpesvirus 4, Human