Tranexamic acid for safer surgery: the time is now.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 36070986.
- Also identified by DOI 10.1016/j.bja.2022.06.024.
- No licence information is recorded for this record.
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Abstract
Tranexamic acid reduces surgical bleeding. Consistent with previous research, the POISE-3 (Peri-Operative Ischemic Evaluation-3) trial found that tranexamic acid reduces major bleeding by 25% and with a low probability of any increase in thromboembolic events. Wider tranexamic acid use will improve surgical safety, avoid unnecessary blood use, reduce the risk of transfusion transmitted infections, and save healthcare funds. 'Consideration of tranexamic acid use' should be included in the safe surgery checklist. We have the evidence, and we need to act on it.
Medical subject headings
- Blood Loss, Surgical
- Tranexamic Acid