A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36097212.
- Also identified by DOI 10.1038/s41592-022-01584-2 and PMC identifier 9466301.
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Abstract
A tissue engineering method using a 3D scaffolding enables the generation of an artificial human thymus from inducible pluripotent stem cells (iPSCs). The artificial thymus can be used to study human T cell development in hematopoietic humanized mice.
Medical subject headings
- Induced Pluripotent Stem Cells
- T-Lymphocytes