Experience Using Adjuvant Bacteriophage Therapy for the Treatment of 10 Recalcitrant Periprosthetic Joint Infections: A Case Series.

Doub, James B; Johnson, Aaron J; Nandi, Sumon; Ng, Vincent; Manson, Theodore; Lee, Myounghee; Chan, Benjamin · Clin Infect Dis · 2023

case_series · Level IV

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Abstract

Periprosthetic joint infections are a devastating complication of joint replacement surgery. One novel therapeutic that has potential to change the current treatment paradigm is bacteriophage therapy. Herein, we discuss our experiences with bacteriophage therapy for 10 recalcitrant periprosthetic joint infections and review the treatment protocols utilized to achieve successful outcomes.

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