CAR T<sub>r</sub><sub>e</sub><sub>g</sub> cells: prime suspects in therapeutic resistance.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 36109644.
- Also identified by DOI 10.1038/s41591-022-01998-7 and PMC identifier 12036812.
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Abstract
Using comprehensive single-cell profiling, two studies reveal the molecular phenotypes of CAR T cells associated with durable response in patients with lymphoma, and highlight the role of CAR regulatory T cells in mediating resistance.
Medical subject headings
- Receptors, Chimeric Antigen