Lupus nephritis transcriptomics across space and time.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 36150761.
- Also identified by DOI 10.1016/j.kint.2022.06.028 and PMC identifier 11639589.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Current immunosuppression regimens for lupus nephritis are incompletely effective, placing patients at risk for poor long-term outcomes. This emphasizes the need to dissect pathogenic mechanisms in lupus nephritis, to inform the development of targeted therapies. In this issue of Kidney International, Parikh et al. performed transcriptomic analysis of pretreatment and posttreatment protocol kidney biopsies, segregated into glomerular and tubulointerstitial compartments, to identify candidate molecular pathways distinguishing treatment responders and nonresponders.
Medical subject headings
- Lupus Nephritis