Remdesivir Resistance in Transplant Recipients With Persistent Coronavirus Disease 2019.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 36156117.
- Also identified by DOI 10.1093/cid/ciac769 and PMC identifier 9619446.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
New mutations conferring resistance to SARS-CoV-2 therapeutics have important clinical implications. We describe the first cases of an independently acquired V792I RNA-dependent RNA polymerase mutation developing in renal transplant recipients after remdesivir exposure. Our work underscores the need for augmented efforts to identify concerning mutations and address their clinical implications.
Medical subject headings
- COVID-19