Time isn't kind to female T-cells.
Where this comes from
- Record sourced from PubMed, PMID 36157102.
- Also identified by DOI 10.1038/s43587-022-00185-0 and PMC identifier 9496640.
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Abstract
While investigating sex-differences in T-cell aging, <i>Mkhikian et al.</i>, identified a role for excessive IL-7 signaling and N-glycan branching in age-related mouse and human female T-cell dysfunction. These findings point to the increasingly-recognized importance of the impact of biological sex on immune aging and delineate new targetable pathways in age-related immune dysfunction.
Medical subject headings
- Aging
- Cellular Senescence