Small wonder: nanoparticles feed hydroxychloroquine to activated neutrophils.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36180549.
- Also identified by DOI 10.1038/s41584-022-00854-9 and PMC identifier 9524339.
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Abstract
Although neutrophils are vital components of the innate immune system, they can also contribute to the inflammation and autoantibody formation that characterize a number of rheumatic diseases. The ability to specifically target neutrophils, and in particular activated neutrophils, could enable the direct delivery of drugs for therapeutic modulation of neutrophil activity.
Medical subject headings
- Hydroxychloroquine
- Nanoparticles