A Theranostic Approach for CAR-T Cell Therapy.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 36250927.
- Also identified by DOI 10.1158/1078-0432.CCR-22-2565.
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Abstract
Fibroblast activation protein (FAP) is frequently expressed in the tumor stroma, whereas expression by normal organs is highly restricted. Despite these promising features, FAP-targeted therapies have shown limited success so far. FAP imaging offers new opportunities to select patients for FAP-targeted therapies and monitor tumor response. See related article by Lee et al., p. 5330.
Medical subject headings
- Gelatinases
- Receptors, Chimeric Antigen