Optical Biometry and IOL Calculation in a Commercially Available Optical Coherence Tomography Device and Comparison With Pentacam AXL.

Abstract

Optical devices are the gold standard for ocular biometry; however, they are unable to obtain high-quality optical coherence tomography (OCT) images. The current study aimed to evaluate ocular measurements and intraocular lens (IOL) calculation used in an anterior/posterior segment OCT device and to compare the results with those of a validated biometer. Prospective evaluation of a diagnostic tool. This study enrolled healthy subjects at the Hygeia Clinic, Gdańsk, Poland, between October 2021 and November 2021. All individuals had ocular biometry measured with a validated biometer (Pentacam AXL) and with a new module of an anterior/posterior segment OCT device (Revo 80, Optopol Technologies). All IOL calculations were performed for the right eye with keratometric values from the Pentacam for one IOL: the Alcon AcrySof IQ SN60WF, with plano target setting. The mean age of the 144 participants was 25.23 ± 7.15 years. The axial length measured with Revo was longer than with Pentacam AXL (24.08 ± 1.13 vs 23.98 ± 1.13; P < .0001), a 0.10 ± 0.04 mm difference. This translated into a significantly lower IOL power to achieve emmetropia for all formulas (-0.34 ± 0.15, -0.32 ± 0.13, -0.34 ± 0.19, and -0.30 ± 0.15 for the Hoffer Q, Holladay I, Haigis, and SRK/T formulas, respectively). The study showed high agreement between the devices: nearly 90% of eyes were within ±0.50 diopters for all of the analyzed formulas (r > 0.99). The present study demonstrates that the results of IOL calculation with the OCT biometer have a very strong correlation with those obtained with the Pentacam AXL; however, axial length measurements and calculated IOL power cannot be considered interchangeable.