Reducing misclassification bias in severe malaria research.

Ippolito, Matthew M; Robinson, Matthew L · Cell Rep Med · 2022

editorial · Level V

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Abstract

By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.<sup>1</sup> increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification.

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