Rapid prototyping of functional acoustic devices using laser manufacturing.

Zhang, Xiang; Son, Rosa; Lin, Yen-Ju; Gill, Alexi; Chen, Shilin; Qi, Tong; Choi, David; Wen, Jing et al. · Lab Chip · 2022

basic_science · Level V

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Abstract

Acoustic patterning of micro-particles has many important biomedical applications. However, fabrication of such microdevices is costly and labor-intensive. Among conventional fabrication methods, photo-lithography provides high resolution but is expensive and time consuming, and not ideal for rapid prototyping and testing for academic applications. In this work, we demonstrate a highly efficient method for rapid prototyping of acoustic patterning devices using laser manufacturing. With this method we can fabricate a newly designed functional acoustic device in 4 hours. The acoustic devices fabricated using this method can achieve sub-wavelength, complex and non-periodic patterning of microparticles and biological objects with a spatial resolution of 60 μm across a large active manipulation area of 10 × 10 mm<sup>2</sup>.

Medical subject headings