Reply to the 'Comment on "Bilayer aggregate microstructure determines viscoelasticity of lung surfactant suspensions"' by J.-F. Berret, DOI: 10.1039/d2sm00653g.
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- Record sourced from PubMed, PMID 36305757.
- Also identified by DOI 10.1039/d2sm01142e and PMC identifier 9833120.
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Abstract
In their comment, Berret suggests that Curosurf, one of three clinical lung surfactant aqueous suspensions examined in the <i>Soft Matter</i>, 2021, <b>17</b>, 5170-51820 is a Newtonian liquid rather than a shear-thinning soft solid with a small, but measurable yield stress. We postulate that these discrepancies may be due to the size of the magnetic wire measurement probe used in their paper (Thai <i>et al.</i>, <i>Colloids Surf., B</i>, 2019, <b>178</b>, 337-345) the diameter of which is similar in size to the Curosurf bilayer agregates (1-10 μm). The cone and plate rheometer used by Ciutara and Zasadzinski measures averaged effects over the entire macroscopic sample. Our combined results point out that the local viscoelastic properties of a moderately dense suspension may be different than its bulk properties.
Medical subject headings
- Pulmonary Surfactants