Too Much Fuel on the Fire? Linking Obesity, Metabolism, and Melanoma Outcomes.

Smalley, Keiran S M · Clin Cancer Res · 2023

editorial · Level V

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Abstract

Patients with metastatic melanoma who are overweight or obese have improved outcomes when treated with immunotherapies or targeted therapies. A recent study provides the first evidence that the host metabolic state influences the tumor metabolic phenotype, with implications for tumor progression and therapeutic response. See related article by Hahn et al., p. 154.

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