Histological Features Associated With Human Mpox Virus Infection in 2022 Outbreak in a Nonendemic Country.

Chalali, Faris; Merlant, Marie; Truong, Audrey; Ghosn, Jade; Phung, Bao-Chau; Mollo, Bastien; Perrineau, Ségolène; Rahi, Mayda et al. · Clin Infect Dis · 2023

case_series · Level IV

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Abstract

Skin histology of papules and pustules from 5 men having sex with men with mpox infection showed viral intracytoplasmic cytopathic changes, interface dermatitis, marked inflammatory dermic infiltrate including superficial neutrophils and perivascular and periadnexal deep lymphocytes. Histologic description of mpox lesions improves our understanding about clinical presentations and may have some therapeutic implications.

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